Profile
Asst Prof Bernett Lee
Co-Principal Investigator
Asst Prof Bernett Lee is a bioinformatician who heads the Centre for Biomedical Informatics at the Lee Kong Chian School of Medicine (LKCMedicine). He has a breadth of experience in both academic and industry settings working on diverse topics including database development and curation, computational drug development and biomedical data analytics. He has a strong interest in the application of computational methods to biomedical problems. This includes the use of web-based interactive visualization methods to facilitate the interpretation of scientific results. His work has been largely collaborative both within
LKCMedicine as well as with clinical and basic science research groups in universities, hospitals and research entities. These collaborations have supported numerous publications. He has also been involved in several grants from the National Research Foundation, A*STAR, Ministry of Education and AI Singapore for data analytic support.
Singapore - NTU
Researchers
HD4
Research Interest
- Application of bioinformatics methods to advance biological research
- Evolution biology using bioinformatics method
Key Publications
Google Scholar Link
S. M. S. Ng et al., “The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS),” Eye, 2023. doi: 10.1038/s41433-023-02472-5.
X. L. Guan et al., “LipidA-IDER to explore the global lipid A repertoire of drug-resistant gram-negative bacteria,” Analytical Chemistry, 2023. doi: 10.1021/acs.analchem.1c03566.
J. Lim et al., “Data-driven analysis of COVID-19 reveals persistent immune abnormalities in convalescent severe individuals,” Frontiers in Immunology, vol. 12, 2021. doi: 10.3389/fimmu.2021.710217.
G. Monaco et al., “RNA-seq signatures normalized by mRNA abundance allow absolute deconvolution of human immune cell types,” Cell Reports, vol. 26, no. 6, 1627–1640.e7, 2019. doi: 10.1016/j.celrep.2019.01.041.
F.-M. Lum et al., “Longitudinal study of cellular and systemic cytokine signatures to define the dynamics of a balanced immune environment during disease manifestation in zika virus-infected patients,” The Journal of Infectious Diseases, vol. 218, no. 5, pp. 814–824, 2018. doi: 10.1093/infdis/jiy225.