Prof John CHAMBERS

Principal Investigator

Prof John Chambers graduated with a BA (first class) from Oxford University. He went on to complete an MBBS and PhD at London University. While in the UK, he led an extensive research programme, while also working as a practising cardiologist with the London North West Hospitals NHS Trust. His clinical activities included the care of acute cardiac patients, elective and acute PCI, and cardiac device implants.

Prof Chambers’ research focuses on the identification of mechanisms that underlie the high rate of cardiovascular disease and diabetes in Asian populations, as well as translational research to improve the prevention and control of these major diseases. Supported by major funding from the EU, and UK and an NMRC STaR Award, he has established and leads large-scale prospective population studies in Europe, South Asia and Singapore. These unique population cohorts have led to the discovery of novel genetic and epigenetic pathways associated with coronary heart disease, type 2 diabetes, obesity, and related metabolic disturbances implicating new molecular pathways underlying these diseases. To date, he has published >30 papers in Nature Genetics and Nature.

As Professor of Cardiovascular Epidemiology at LKCMedicine, Prof Chambers focuses on identifying new strategies for the prediction and prevention of cardiovascular disease and diabetes. He aims to inspire a new generation of researchers who will continue his efforts in identifying novel ways to predict and prevent disease. He hopes to achieve these through the various research networks he has established in the region, the research platform at LKCMedicine and the clinical platform at local healthcare facilities, in particular, those under the National Healthcare Group.

Singapore

Researchers

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